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KMID : 0613820080180060852
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Journal of Life Science
2008 Volume.18 No. 6 p.852 ~ p.857
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Effect of Bulnesia sarmienti Water Extract on Lipid Metabolism in Type-1 Diabetic Rats
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Park Chang-Ho
Kim Jung-Ok
Lee Gee-Dong
Kim Kil-Soo
Hong Joo-Heon
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Abstract
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The effects of Bulnesia sarmienti water extract on lipid metabolism were investigated in type-1 diabetes rats. The rats were fed a basal diet and B. sarmienti water extract for 8 weeks. The rats were randomly assigned to each treatment group: normal, control, three kinds of treatment group (BW0: 0.45 ㎎/㎖, BW1: 0.9 ㎎/㎖, BW2: 1.8 ㎎/㎖). After 8 weeks of experimental diets consumption, the body weights and food efficiency ratio of B. sarmienti water extract fed groups were not change with those in the control group. The concentration in plasma total-cholesterol, LDL-cholesterol, triglyceride were significantly decrease in the B. sarmienti water extract groups compared with those in the control group. Although it was not possible to observe blood glucose control effects of eight weeks of B. sarmienti water extract feeds in type-1 diabetes model, it was discovered that the feeds are highly effective in lowering the levels of blood lipid substances triglycerides, total-cholesterol, and LDL-cholesterol.
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KEYWORD
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Bulnesiasarmienti, lipidmetabolism, total-cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride
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